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Base-Catalyzed Synthesis of N-Aryl Thioacetamides from Multicomponent Reaction of Phenylacetylenes, Sulfur and Anilines

Hang Nguyen, M. and Sam Nguyen, H. and Anh Nguyen, L. and Ngoc Nguyen, B. and Thuong Cao, H. and Hung Mac, D. and Binh Nguyen, T. (2024) Base-Catalyzed Synthesis of N-Aryl Thioacetamides from Multicomponent Reaction of Phenylacetylenes, Sulfur and Anilines. European Journal of Organic Chemistry. ISSN 1434193X

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Abstract

In the presence of a base catalyst (20 mol ) such as DBU, DABCO or Na2S ⋅ 3H2O/N-methylpyrrolidone, phenylacetylenes were found to efficiently undergo sulfurative amination with elemental sulfur and anilines under neat conditions, leading to N-aryl thioamides with complete atom efficiency. © 2024 Wiley-VCH GmbH.

Item Type: Article
Divisions: Faculties > Faculty of Physical and Chemical Engineering
Identification Number: 10.1002/ejoc.202301319
Uncontrolled Keywords: atom economy; elemental sulfur; multicomponent reaction; thioamide; thioketene
URI: http://eprints.lqdtu.edu.vn/id/eprint/11083

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