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Occurrence and risk of human exposure to organophosphate flame retardants in indoor air and dust in Hanoi, Vietnam

Hoang, M.T.T. and Le, G.T. and Kiwao, K. and Duong, H.T. and Nguyen, T.Q. and Phan, T.Q. and Bui, M.Q. and Truong, D.A. and Trinh, H.T. (2023) Occurrence and risk of human exposure to organophosphate flame retardants in indoor air and dust in Hanoi, Vietnam. Chemosphere, 328: 138597. ISSN 00456535

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Abstract

The presence and distribution of thirteen organophosphate flame retardants (OPFRs) were investigated in indoor air and dust samples collected in Hanoi, Vietnam. The total OPFRs (ƩOPFRs) concentrations in indoor air and dust samples were 42.3–358 ng m−3 (median 101 ng m−3) and 1290–17,500 ng g−1 (median 7580 ng g−1), respectively. The profile of OPFRs in both indoor air and dust indicated that tris(1-chloro-2-propyl) phosphate (TCIPP) was the most dominant compound with a median concentration of 75.3 ng m−3 and 3620 ng g−1, contributing 75.2 and 46.1 to ƩOPFRs concentrations in indoor air and dust, respectively, followed by tris(2-butoxyethyl) phosphate (TBOEP), with a median concentration of 16.3 ng m−3 and 2500 ng g−1, contributing 14.1 and 33.6 to ƩOPFRs concentrations in indoor air and dust, respectively. The levels of OPFRs in the indoor air samples and corresponding indoor dust samples showed a strong positive correlation. The total estimated daily intakes (EDItotal) of ƩOPFRs (via air inhalation, dust ingestion, and dermal absorption) for adults and toddlers under the median and high exposure scenarios were 36.7 and 160 ng kg−1 d−1, and 266 and 1270 ng kg−1 d−1, respectively. Among the investigated exposure pathways, dermal absorption was a primary exposure pathway to OPFRs for both toddlers and adults. The hazard quotients (HQ) ranged from 5.31 × 10−8 to 6.47 × 10−2 (<1), and the lifetime cancer risks (LCR) were from 2.05 × 10−11 to 7.37 × 10−8 (<10−6), indicating that human health risks from exposure to OPFRs in indoor environments are not significant. © 2023

Item Type: Article
Divisions: Institutes > Institute of Techniques for Special Engineering
Identification Number: 10.1016/j.chemosphere.2023.138597
Uncontrolled Keywords: Air intakes; Dust; Flame retardants; Health risks, Air samples; Dermal absorption; Dust samples; Human exposures; Indoor air; Indoor dust; Median concentration; Organophosphate flame retardants; Risks assessments; Viet Nam, Risk assessment, flame retardant; organophosphate, cancer; dose-response relationship; dust; flame retardant; indoor air; organophosphate; public health; risk assessment, adult; air sampling; ambient air; Article; cancer risk; child; concentration (parameter); controlled study; dust exposure; estimated daily intake; health hazard; human; indoor environment; ingestion; inhalation; risk assessment; skin absorption; toddler; Viet Nam, Hanoi; Viet Nam
URI: http://eprints.lqdtu.edu.vn/id/eprint/10800

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